Monday 30 April 2012

Hizentra


Pronunciation: i-MUNE GLOB-ue-lin
Generic Name: Immune Globulin (Human)
Brand Name: Hizentra


Hizentra is used for:

Providing antibodies to help prevent infection in certain patients who have a weakened immune system. It may also be used for other conditions as determined by your doctor.


Hizentra is an immune globulin. It works by providing antibodies, which fight infection.


Do NOT use Hizentra if:


  • you are allergic to any ingredient in Hizentra (including polysorbate 80)

  • you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to blood or products that are produced from blood

  • you have high levels of proline in the blood

  • you have low immunoglobulin A (IgA) levels, antibodies to IgA, or a history of allergic reaction to IgA

Contact your doctor or health care provider right away if any of these apply to you.



Before using Hizentra:


Some medical conditions may interact with Hizentra. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have low IgA levels or antibodies to IgA

  • if you have recently received any vaccinations

  • if you have heart problems, blood vessel problems (eg, narrowed arteries), thick blood, a blood clotting disorder, or a history of stroke, heart attack, or blood clots

  • if you have kidney problems, diabetes, dehydration or low blood volume, a blood infection, abnormal proteins in the blood, or asthma

  • if you have been or may be exposed to measles

  • if you will be confined to a bed or a chair for a long period of time

Some MEDICINES MAY INTERACT with Hizentra. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Medicines that may harm the kidney (eg, aminoglycoside antibiotics [eg, gentamicin], amphotericin B, cyclosporine, nonsteroidal anti-inflammatory drugs [NSAIDs] [eg, ibuprofen], tacrolimus, vancomycin) because the risk of kidney side effects may be increased. Ask your doctor if you are unsure if any of your medicines might harm the kidney

  • Hydantoins (eg, phenytoin) because unexpected allergic reactions may occur

  • Live vaccines (eg, measles, mumps, rubella) because their effectiveness may be decreased by Hizentra

This may not be a complete list of all interactions that may occur. Ask your health care provider if Hizentra may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Hizentra:


Use Hizentra as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An extra patient leaflet is available with Hizentra. Talk to your pharmacist if you have questions about this information.

  • Hizentra is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Hizentra at home, a health care provider will teach you how to use it. Be sure you understand how to use Hizentra. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

  • Do not use Hizentra if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

  • Do not shake Hizentra.

  • Do not mix Hizentra with any other medicine.

  • Inject Hizentra under the skin, NOT into a muscle or vein. Inject into the abdomen, thigh, upper arm, or outer hip. If more than 1 injection site is used at the same time, be sure there are at least 2 inches between injection sites. Rotate injection sites with each dose of Hizentra.

  • Throw away any medicine that is left in the vial after you use a dose of Hizentra.

  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

  • If you miss a dose of Hizentra, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Hizentra.



Important safety information:


  • Hizentra may cause dizziness or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Hizentra with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Aseptic meningitis syndrome (AMS) has been reported to occur rarely in association with the use of Hizentra. This usually begins within several hours to 2 days following treatment. Symptoms include severe headache, neck stiffness, unusual drowsiness, fever, painful eye movements, sensitivity to light, nausea, and vomiting.

  • Live vaccines (eg, measles, mumps) may not work as well while you are using Hizentra. Talk with your doctor before you receive any vaccine.

  • Hizentra is made from human plasma. There is an extremely low risk of developing a viral infection or Creutzfeldt-Jakob disease (CJD) after using Hizentra. Discuss any questions or concerns with your doctor.

  • Hizentra may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Hizentra.

  • Lab tests, including kidney function, blood thickness, and antibody levels, may be performed while you use Hizentra. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Hizentra with caution in the ELDERLY; they may be more sensitive to its effects, especially kidney failure or blood clots.

  • Use Hizentra with extreme caution in NEWBORNS or INFANTS; safety and effectiveness in these children have not been established.

  • PREGNANCY and BREAST-FEEDING: It is not known if Hizentra can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Hizentra while you are pregnant. It is not known if Hizentra is found in breast milk. If you are or will be breast-feeding while you use Hizentra, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Hizentra:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Cough; diarrhea; headache; muscle, joint, or back pain; nausea; pain, swelling, redness, heat, or itching at the injection site; stomach upset; tiredness; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; itching; hives; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, hands, face, lips, eyes, throat, or tongue); calf pain or tenderness; chest pain or tightness; confusion; coughing up blood; dark urine; dizziness; fainting; fast or irregular heartbeat; fever or chills; numbness of an arm or a leg; one-sided weakness; red, swollen, blistered, or peeling skin; seizures; severe headache or stomach pain; shortness of breath or trouble breathing; speech problems; symptoms of kidney problems (eg, decreased urination, lower back or flank pain, swelling or bloating, sudden weight gain); unusual bruising or bleeding; unusual tiredness or weakness; vision problems; wheezing; yellowing of the skin or eyes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Hizentra:

Store Hizentra at room temperature up to 77 degrees F (25 degrees C). Do not freeze. Do not use Hizentra if it has been frozen or if the expiration date on the container has passed. Keep Hizentra out of the reach of children and away from pets.


General information:


  • If you have any questions about Hizentra, please talk with your doctor, pharmacist, or other health care provider.

  • Hizentra is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Hizentra. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Hizentra resources


  • Hizentra Use in Pregnancy & Breastfeeding
  • Hizentra Drug Interactions
  • Hizentra Support Group
  • 5 Reviews for Hizentra - Add your own review/rating


  • Hizentra Prescribing Information (FDA)

  • Hizentra Consumer Overview

  • Hizentra Advanced Consumer (Micromedex) - Includes Dosage Information

  • Immune Globulin Subcutaneous Professional Patient Advice (Wolters Kluwer)

  • Vivaglobin Prescribing Information (FDA)

  • Vivaglobin Consumer Overview



Compare Hizentra with other medications


  • Autoimmune Neutropenia
  • Bone Marrow Transplantation
  • Chronic Inflammatory Demyelinating Polyradiculoneuropathy
  • Chronic Lymphocytic Leukemia
  • Evan's Syndrome
  • HIV Infection
  • Idiopathic Thrombocytopenic Purpura
  • Kawasaki Disease
  • Myasthenia Gravis
  • Polymyositis/Dermatomyositis
  • Primary Immunodeficiency Syndrome

Saturday 28 April 2012

Laronidase


Pronunciation: lar-ON-i-dase
Generic Name: Laronidase
Brand Name: Aldurazyme

Serious and sometimes fatal allergic reactions have occurred with use of Laronidase. Tell your doctor right away if you develop rash; itching; fast or difficult breathing; chest tightness; severe dizziness; swelling of hands, face, lips, eyes, throat, or tongue; difficulty swallowing; or hoarseness.


Tell your doctor if you have lung or breathing problems. You may be at risk for severe worsening of your breathing problems if you experience an allergic reaction to Laronidase.





Laronidase is used for:

Treating patients with Hurler and Hurler-Scheie forms of mucopolysaccharidosis I (MPS I), and patients with Scheie form who have moderate to severe symptoms.


Laronidase is a glycoprotein. It works by providing the enzyme alpha-L-iduronidase to the body.


Do NOT use Laronidase if:


  • you are allergic to any ingredient in Laronidase

Contact your doctor or health care provider right away if this applies to you.



Before using Laronidase:


Some medical conditions may interact with Laronidase. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have lung or breathing problems (eg, bronchitis)

Some MEDICINES MAY INTERACT with Laronidase. However, no specific interactions with Laronidase are known at this time.


Ask your health care provider if Laronidase may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Laronidase:


Use Laronidase as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Laronidase is given as an injection at your doctor's office, hospital, or clinic.

  • If you miss a dose of Laronidase, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Laronidase.



Important safety information:


  • Serious and sometimes fatal allergic reactions have occurred with use of Laronidase. You will need to take certain other medicines before you receive Laronidase in order to decrease the risk of allergic reaction. Discuss any questions or concerns with your doctor.

  • Laronidase should be used with extreme caution in CHILDREN younger than 5 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Laronidase while you are pregnant. It is not known if Laronidase is found in breast milk. If you are or will be breast-feeding while you use Laronidase, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Laronidase:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Flushing; headache; mild redness, stinging, or pain at the injection site.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; cough; diarrhea; dizziness; fast or slow heartbeat; fever, chills, or sore throat; joint pain; nausea; numbness or tingling of the skin; rapid breathing; severe headache; stomach pain; unusual bruising or bleeding; unusual swelling; vision changes; vomiting.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Laronidase side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Laronidase:

Laronidase is usually handled and stored by a health care provider. If you are using Laronidase at home, store Laronidase as directed by your pharmacist or health care provider.


General information:


  • If you have any questions about Laronidase, please talk with your doctor, pharmacist, or other health care provider.

  • Laronidase is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Laronidase. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Laronidase resources


  • Laronidase Side Effects (in more detail)
  • Laronidase Use in Pregnancy & Breastfeeding
  • Laronidase Drug Interactions
  • Laronidase Support Group
  • 0 Reviews for Laronidase - Add your own review/rating


  • Laronidase Professional Patient Advice (Wolters Kluwer)

  • Laronidase Monograph (AHFS DI)

  • laronidase Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information

  • Aldurazyme Prescribing Information (FDA)

  • Aldurazyme Consumer Overview



Compare Laronidase with other medications


  • Mucopolysaccharidosis Type I

Friday 20 April 2012

halazepam


Generic Name: halazepam (hal AZ e pam)

Brand Names: Paxipam


What is halazepam?

Halazepam is not commercially available in the United States.


Halazepam is in a class of drugs called benzodiazepines. Halazepam affects chemicals in the brain that may become unbalanced and cause anxiety.


Halazepam is used to relieve anxiety, nervousness, and tension associated with anxiety disorders.


Halazepam may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about halazepam?


Halazepam is not commercially available in the United States.


Use caution when driving, operating machinery, or performing other hazardous activities. Halazepam will cause drowsiness and may cause dizziness. If you experience drowsiness or dizziness, avoid these activities. Avoid alcohol while taking halazepam. Alcohol may increase drowsiness and dizziness caused by halazepam. Halazepam is habit forming. You can become physically and psychologically dependent on the medication. Do not take more than the prescribed amount of medication or take it for longer than is directed by your doctor. Withdrawal effects may occur if halazepam is stopped suddenly after several weeks of continuous use. Your doctor may recommend a gradual reduction in dose.

What should I discuss with my healthcare provider before taking halazepam?


Do not take halazepam if you have narrow-angle glaucoma. Halazepam may worsen this condition.

Before taking this medication, tell your doctor if you



Video: Treatment for Depression







Treatments for depression are getting better everyday and there are things you can start doing right away.





  • have kidney disease;

  • have liver disease;


  • have asthma, bronchitis, emphysema, or another respiratory disease; or




  • are depressed or have suicidal thoughts.



You may not be able to take halazepam, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.


It is not known whether halazepam will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. It is not known whether halazepam passes into breast milk. Do not take halazepam without first talking to your doctor if you are breast-feeding a baby. If you are over 65 years of age, you may be more likely to experience side effects from halazepam. You may require a lower dose of this medication.

How should I take halazepam?


Take halazepam exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.


Take each dose with a full glass of water.

Do not take more than is prescribed for you.


Halazepam is habit forming. You can become physically and psychologically dependent on the medication. Do not take more than the prescribed amount of medication or take it for longer than is directed by your doctor. Withdrawal effects may occur if halazepam is stopped suddenly after several weeks of continuous use. Your doctor may recommend a gradual reduction in dose. Store halazepam at room temperature away from moisture and heat.

See also: Halazepam dosage (in more detail)

What happens if I miss a dose?


Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose. Do not take a double dose of this medication. A double dose could be very dangerous.


What happens if I overdose?


Seek emergency medical attention.

Symptoms of a halazepam overdose include sleepiness, dizziness, confusion, a slow heart beat, difficulty breathing, difficulty walking and talking, an appearance of being drunk, and unconsciousness.


What should I avoid while taking halazepam?


Use caution when driving, operating machinery, or performing other hazardous activities. Halazepam will cause drowsiness and may cause dizziness. If you experience drowsiness or dizziness, avoid these activities. Avoid alcohol while taking halazepam. Alcohol may increase drowsiness and dizziness caused by halazepam.

Halazepam may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.


Halazepam side effects


If you experience any of the following serious side effects, stop taking halazepam and seek emergency medical attention:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, face, or tongue; or hives);




  • sores in the mouth or throat;




  • yellowing of the skin or eyes;




  • a rash;




  • hallucinations or severe confusion; or




  • changes in vision.



Other, less serious side effects may be more likely to occur. Continue to take halazepam and talk to your doctor if you experience



  • drowsiness, dizziness, or clumsiness;




  • depression;




  • nausea, vomiting, diarrhea, or constipation;




  • difficulty urinating;




  • vivid dreams;




  • headache;




  • dry mouth;




  • decreased sex drive; or




  • changes in behavior.



Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


Halazepam Dosing Information


Usual Adult Dose for Anxiety:

Initial dose: 20 mg orally 3 times a day.
Maximum Dose: 160 mg

Usual Geriatric Dose for Anxiety:

Initial dose: 20 mg orally twice a day.


What other drugs will affect halazepam?


Halazepam may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.


Antacids may decrease the effects of halazepam. Separate doses of an antacid and halazepam by several hours whenever possible.


Drugs other than those listed here may also interact with halazepam. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.



More halazepam resources


  • Halazepam Side Effects (in more detail)
  • Halazepam Dosage
  • Halazepam Use in Pregnancy & Breastfeeding
  • Halazepam Drug Interactions
  • Halazepam Support Group
  • 0 Reviews for Halazepam - Add your own review/rating


Compare halazepam with other medications


  • Anxiety


Where can I get more information?


  • Your pharmacist has additional information about halazepam written for health professionals that you may read.

What does my medication look like?


Halazepam is not commercially available in the United States.


See also: halazepam side effects (in more detail)


Chlorhexidine Liquid


Pronunciation: klor-HEX-ih-deen
Generic Name: Chlorhexidine
Brand Name: Examples include Betasept and Hibiclens


Chlorhexidine Liquid is used for:

Cleansing skin and wound areas. It may also be used for other conditions as determined by your doctor.


Chlorhexidine Liquid is a topical antimicrobial. It works by reacting with the microbial cell surface, destroying the cell membrane, and killing the cell.


Do NOT use Chlorhexidine Liquid if:


  • you are allergic to any ingredient in Chlorhexidine Liquid

Contact your doctor or health care provider right away if any of these apply to you.



Before using Chlorhexidine Liquid:


Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Chlorhexidine Liquid. However, no specific interactions with Chlorhexidine Liquid are known at this time.


Ask your health care provider if Chlorhexidine Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Chlorhexidine Liquid:


Use Chlorhexidine Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • To cleanse the skin, thoroughly rinse the area to be cleansed with water. Apply the minimum amount necessary to cover the skin or wound area and wash gently. Rinse thoroughly.

  • If you miss a dose of Chlorhexidine Liquid, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Chlorhexidine Liquid.



Important safety information:


  • Chlorhexidine Liquid is for external use only. Avoid contact with eyes, ears, and mouth. If Chlorhexidine Liquid contacts any of these areas, rinse out promptly and thoroughly with water.

  • Chlorhexidine Liquid may stain clothing.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Chlorhexidine Liquid while you are pregnant. It is not known if Chlorhexidine Liquid is found in breast milk. If you are or will be breast-feeding while you use Chlorhexidine Liquid, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Chlorhexidine Liquid:


All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Skin irritation, itching, or redness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Chlorhexidine side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Chlorhexidine Liquid may be harmful if swallowed.


Proper storage of Chlorhexidine Liquid:

Store Chlorhexidine Liquid at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Avoid excessive heat above 104 degrees F (40 degrees C), and light. Keep Chlorhexidine Liquid out of the reach of children and away from pets.


General information:


  • If you have any questions about Chlorhexidine Liquid, please talk with your doctor, pharmacist, or other health care provider.

  • Chlorhexidine Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Chlorhexidine Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Chlorhexidine resources


  • Chlorhexidine Side Effects (in more detail)
  • Chlorhexidine Use in Pregnancy & Breastfeeding
  • Chlorhexidine Support Group
  • 1 Review for Chlorhexidine - Add your own review/rating


Compare Chlorhexidine with other medications


  • Gingivitis
  • Mucositis
  • Periodontitis

Wednesday 18 April 2012

Chlorpheniramine Syrup



Pronunciation: klor-fen-IHR-ah-meen
Generic Name: Chlorpheniramine
Brand Name: Examples include Aller-Chlor and Chlor-Trimeton


Chlorpheniramine Syrup is used for:

Relieving symptoms of sinus congestion, sinus pressure, runny nose, watery eyes, itching of the nose and throat, and sneezing due to upper respiratory infections (eg, colds), allergies, and hay fever. It may also be used for other conditions as determined by your doctor.


Chlorpheniramine Syrup is an antihistamine. It works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing.


Do NOT use Chlorpheniramine Syrup if:


  • you are allergic to any ingredient in Chlorpheniramine Syrup

  • you are taking sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Chlorpheniramine Syrup:


Some medical conditions may interact with Chlorpheniramine Syrup. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, plan to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a fast, slow, or irregular heartbeat

  • if you have a history of asthma, lung problems (eg, emphysema), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, a blockage of your stomach or intestines, ulcers, a blockage of your bladder, trouble urinating, an enlarged prostate, seizures, or an overactive thyroid

Some MEDICINES MAY INTERACT with Chlorpheniramine Syrup. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Furazolidone, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects of Chlorpheniramine Syrup may be increased

  • Hydantoins (eg, phenytoin) because side effects may be increased by Chlorpheniramine Syrup

This may not be a complete list of all interactions that may occur. Ask your health care provider if Chlorpheniramine Syrup may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Chlorpheniramine Syrup:


Use Chlorpheniramine Syrup as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Chlorpheniramine Syrup may be taken with or without food.

  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • If you miss a dose of Chlorpheniramine Syrup, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Chlorpheniramine Syrup.



Important safety information:


  • Chlorpheniramine Syrup may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Chlorpheniramine Syrup. Using Chlorpheniramine Syrup alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Do NOT exceed the recommended dose or take Chlorpheniramine Syrup for longer than prescribed without checking with your doctor.

  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.

  • Chlorpheniramine Syrup may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Chlorpheniramine Syrup. Use a sunscreen or protective clothing if you must be outside for a prolonged period.

  • If you are scheduled for allergy skin testing, do not take Chlorpheniramine Syrup for several days before the test because it may decrease your response to the skin tests.

  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Chlorpheniramine Syrup.

  • Use Chlorpheniramine Syrup with caution in the ELDERLY because they may be more sensitive to its effects.

  • Caution is advised when using Chlorpheniramine Syrup in CHILDREN because they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Chlorpheniramine Syrup, discuss with your doctor the benefits and risks of using Chlorpheniramine Syrup during pregnancy. It is unknown if Chlorpheniramine Syrup is excreted in breast milk. Do not breast-feed while taking Chlorpheniramine Syrup.


Possible side effects of Chlorpheniramine Syrup:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Chlorpheniramine side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; and vomiting.


Proper storage of Chlorpheniramine Syrup:

Store Chlorpheniramine Syrup at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Chlorpheniramine Syrup out of the reach of children and away from pets.


General information:


  • If you have any questions about Chlorpheniramine Syrup, please talk with your doctor, pharmacist, or other health care provider.

  • Chlorpheniramine Syrup is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Chlorpheniramine Syrup. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Chlorpheniramine resources


  • Chlorpheniramine Side Effects (in more detail)
  • Chlorpheniramine Use in Pregnancy & Breastfeeding
  • Drug Images
  • Chlorpheniramine Drug Interactions
  • Chlorpheniramine Support Group
  • 18 Reviews for Chlorpheniramine - Add your own review/rating


Compare Chlorpheniramine with other medications


  • Allergic Reactions
  • Cold Symptoms
  • Hay Fever
  • Urticaria

Monday 16 April 2012

Sporanox


Generic Name: itraconazole (IT ra KON a zole)

Brand Names: Sporanox, Sporanox PulsePak


What is itraconazole?

Itraconazole is an antifungal medication.


Itraconazole is used to treat infections caused by fungus, which can invade any part of the body including the lungs, mouth or throat, toenails, or fingernails.


Itraconazole may also be used for purposes not listed in this medication guide.


What is the most important information I should know about itraconazole?


Do not take this medication if you are allergic to itraconazole or similar medications such as fluconazole (Diflucan) or ketoconazole (Extina, Ketozole, Nizoral, Xolegal), if you have ever had congestive heart failure, or if you are pregnant or may become pregnant during treatment. There are many other drugs that can cause serious or life threatening medical problems if you take them together with itraconazole. This includes cisapride (Propulsid), dihydroergotamine (D.H.E. 45, Migranal), dofetilide (Tikosyn), ergonovine (Ergotrate), ergotamine (Ergomar), lovastatin (Advicor, Altocor, Altoprev, Mevacor), methylergonovine (Methergine), midazolam (Versed), nisoldipine (Sular), pimozide (Orap), quinidine (Quin-G), simvastatin (Zocor, Simcor, Vytorin), and triazolam (Halcion).

Before taking itraconazole, tell your doctor if you have heart disease, a history of stroke, a heart rhythm disorder, kidney or liver disease, a breathing disorder, cystic fibrosis, or a history of "Long QT syndrome."


Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Itraconazole will not treat a viral infection such as the common cold or flu.

What should I discuss with my healthcare provider before taking itraconazole?


Do not take this medication if you are allergic to itraconazole or similar medications such as fluconazole (Diflucan) or ketoconazole (Extina, Ketozole, Nizoral, Xolegal), if you have ever had congestive heart failure, or if you are pregnant or may become pregnant during treatment. There are many other drugs that can cause serious or life threatening medical problems if you take them together with itraconazole. The following drugs should not be used while you are taking itraconazole:

  • cisapride (Propulsid);




  • dofetilide (Tikosyn);




  • lovastatin (Advicor, Altocor, Altoprev, Mevacor) or simvastatin (Zocor, Simcor, Vytorin);




  • midazolam (Versed) or triazolam (Halcion);




  • nisoldipine (Sular);




  • pimozide (Orap);




  • quinidine (Quin-G); and




  • ergot medicines such as dihydroergotamine (D.H.E. 45, Migranal), ergonovine (Ergotrate), ergotamine (Ergomar, Cafergot, Ercaf, Migergot), or methylergonovine (Methergine).



To make sure you can safely take itraconazole, tell your doctor if you have any of these other conditions:



  • heart disease, a heart rhythm disorder, circulation problems, or a history of stroke;




  • chronic obstructive pulmonary disease (COPD) or other breathing disorder;




  • kidney disease;




  • liver disease;




  • cystic fibrosis; or




  • a personal or family history of "Long QT syndrome."




FDA pregnancy category C. It is not known whether itraconazole will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Itraconazole passes into breast milk and can harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take itraconazole?


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


The itraconazole tablet should be taken after a full meal. Take itraconazole oral solution (liquid) on an empty stomach, at least 1 hour before or 2 hours after a meal. Swish the liquid in your mouth for several seconds before swallowing it.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.


Itraconazole capsules should not be used in place of itraconazole oral solution (liquid) if that is what your doctor has prescribed. Make sure you have received the correct type of this medication at the pharmacy and ask the pharmacist if you have any questions. Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Itraconazole will not treat a viral infection such as the common cold or flu.

To be sure this medication is not causing harmful effects, your liver function will need to be checked with frequent blood tests. Visit your doctor regularly.


Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?


Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking itraconazole?


Avoid taking antacids or stomach acid reducers (Tagamet, Pepcid, Axid, Zantac, and others) within 1 hour before or 2 hours after you take itraconazole. These medications can make it harder for your body to absorb itraconazole.


Itraconazole side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

  • fever;




  • feeling short of breath, even with mild exertion;




  • swelling, rapid weight gain;




  • problems with hearing;




  • numbness or tingly feeling;




  • pain or burning when you urinate;




  • nausea, pain in your upper stomach, itching, loss of appetite, weakness, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or




  • severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate.



Less serious side effects may include:



  • diarrhea, constipation, mild stomach pain;




  • mild itching or skin rash;




  • headache, dizziness; or




  • runny nose or other cold symptoms.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect itraconazole?


Many drugs can interact with itraconazole. Below is just a partial list. Tell your doctor if you are using:



  • a blood thinner such as warfarin (Coumadin);




  • cancer medications;




  • cholesterol medications such as atorvastatin (Lipitor);




  • cyclosporine (Gengraf, Sandimmune, Neoral);




  • diabetes medication you take by mouth;




  • digoxin (digitalis, Lanoxin);




  • disopyramide (Norpace);




  • fentanyl (Actiq, Duragesic);




  • isoniazid (for treating tuberculosis);




  • rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, Rifater, Rifamate), or rifapentine (Priftin);




  • sirolimus (Rapamune) or tacrolimus (Prograf);




  • an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), or telithromycin (Ketek);




  • an antifungal medication such as clotrimazole (Mycelex Troche), ketoconazole (Nizoral), or voriconazole (Vfend);




  • an antidepressant such as nefazodone, paroxetine (Paxil), or sertraline (Zoloft);




  • a barbiturate such as amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Solfoton);




  • heart or blood pressure medications such as amlodipine (Norvasc), diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others;




  • HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), efavirenz (Sustiva), etravirine (Intelence), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), saquinavir (Invirase, Fortovase), or ritonavir (Norvir, Kaletra);




  • a sedative such as alprazolam (Xanax), diazepam (Valium); or




  • seizure medication such as carbamazepine (Carbatrol, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), or phenytoin (Dilantin), or primidone (Mysoline).




This list is not complete and there are many other drugs that can interact with itraconazole. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

More Sporanox resources


  • Sporanox Side Effects (in more detail)
  • Sporanox Use in Pregnancy & Breastfeeding
  • Drug Images
  • Sporanox Drug Interactions
  • Sporanox Support Group
  • 8 Reviews for Sporanox - Add your own review/rating


  • Sporanox Monograph (AHFS DI)

  • Sporanox Prescribing Information (FDA)

  • Sporanox Consumer Overview

  • Sporanox Advanced Consumer (Micromedex) - Includes Dosage Information

  • Sporanox MedFacts Consumer Leaflet (Wolters Kluwer)

  • Itraconazole Prescribing Information (FDA)

  • Itraconazole Professional Patient Advice (Wolters Kluwer)

  • Sporanox PulsePak MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Sporanox with other medications


  • Aspergillosis, Aspergilloma
  • Blastomycosis
  • Candida Infections, Systemic
  • Candida Urinary Tract Infection
  • Coccidioidomycosis
  • Cryptococcosis
  • Dermatophytosis
  • Esophageal Candidiasis
  • Febrile Neutropenia
  • Histoplasmosis
  • Onychomycosis, Fingernail
  • Onychomycosis, Toenail
  • Oral Thrush
  • Paracoccidioidomycosis
  • Sporotrichosis
  • Tinea Capitis
  • Tinea Versicolor
  • Vaginal Yeast Infection


Where can I get more information?


  • Your pharmacist can provide more information about itraconazole.

See also: Sporanox side effects (in more detail)


Thursday 12 April 2012

ceftaroline


Generic Name: ceftaroline (SEF ta ROE leen)

Brand Names: Teflaro


What is ceftaroline?

Ceftaroline is in a group of drugs called cephalosporin (SEF a low spor in) antibiotics. It works by fighting bacteria in your body.


Ceftaroline is used to treat skin infections or pneumonia caused by bacteria.


Ceftaroline may also be used for purposes not listed in this medication guide.


What is the most important information I should know about ceftaroline?


You should not use this medication if you are allergic to ceftaroline, or to similar antibiotics, such as Ceftin, Cefzil, Keflex, and others.

Before using this medication, tell your doctor if you are allergic to any drugs (especially penicillin). Also tell your doctor if you have kidney disease or a history of intestinal problems.


Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Ceftaroline will not treat a viral infection such as the common cold or flu.


Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop using ceftaroline and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.


What should I discuss with my healthcare provider before using ceftaroline?


You should not use this medication if you are allergic to ceftaroline or to other cephalosporin antibiotics, such as:

  • cefaclor (Raniclor);




  • cefadroxil (Duricef);




  • cefazolin (Ancef);




  • cefdinir (Omnicef);




  • cefditoren (Spectracef);




  • cefpodoxime (Vantin);




  • cefprozil (Cefzil);




  • ceftibuten (Cedax);




  • cefuroxime (Ceftin);




  • cephalexin (Keflex); or




  • cephradine (Velosef); and others.



To make sure you can safely use ceftaroline, tell your doctor if you have any of these other conditions:


  • kidney disease (or if you are on dialysis);


  • a history of intestinal problems, such as colitis; or




  • if you are allergic to any drugs (especially penicillin antibiotics).




FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether ceftaroline passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How is ceftaroline given?


Ceftaroline is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.


Ceftaroline is usually given every 12 hours for 5 to 14 days. Follow your doctor's instructions. This medicine must be given slowly, and the IV infusion can take up at least 1 hour to complete.


Ceftaroline is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine.


Prepare your dose in a syringe only when you are ready to give yourself an injection. Ceftaroline should look clear or yellow in color. Do not use the medication if it has changed colors or has particles in it. Call your doctor for a new prescription.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Ceftaroline will not treat a viral infection such as the common cold or flu.


Store in the refrigerator. Do not freeze.

What happens if I miss a dose?


Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using ceftaroline?


Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop using ceftaroline and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.


Ceftaroline side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

  • diarrhea that is watery or bloody;




  • chest pain;




  • fever, chills, body aches, flu symptoms;




  • unusual bleeding;




  • seizure (convulsions);




  • pale or yellowed skin, dark colored urine, fever, confusion or weakness;




  • jaundice (yellowing of the skin or eyes);




  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;




  • increased thirst, loss of appetite, swelling, weight gain, feeling short of breath, urinating less than usual or not at all; or




  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling).



Less serious side effects may include:



  • nausea, vomiting, constipation, mild diarrhea;




  • dizziness; or




  • mild itching.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Ceftaroline Dosing Information


Usual Adult Dose for Skin and Structure Infection:

600 mg IV, infused over 1 hour, every 12 hours for 5 to 14 days

Usual Adult Dose for Pneumonia:

Community acquired: 600 mg IV, infused over 1 hour, every 12 hours for 5 to 7 days


What other drugs will affect ceftaroline?


There may be other drugs that can interact with ceftaroline. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More ceftaroline resources


  • Ceftaroline Side Effects (in more detail)
  • Ceftaroline Dosage
  • Ceftaroline Use in Pregnancy & Breastfeeding
  • Ceftaroline Drug Interactions
  • Ceftaroline Support Group
  • 0 Reviews for Ceftaroline - Add your own review/rating


  • ceftaroline Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information

  • Ceftaroline MedFacts Consumer Leaflet (Wolters Kluwer)

  • Ceftaroline Fosamil Monograph (AHFS DI)

  • Teflaro Prescribing Information (FDA)

  • Teflaro Consumer Overview



Compare ceftaroline with other medications


  • Pneumonia
  • Skin and Structure Infection


Where can I get more information?


  • Your pharmacist can provide more information about ceftaroline.

See also: ceftaroline side effects (in more detail)


Tuesday 3 April 2012

Cloxapen


Generic Name: cloxacillin (klox a SILL in)

Brand Names: Cloxapen, Tegopen


What is Cloxapen (cloxacillin)?

Cloxacillin is an antibiotic in the class of drugs called penicillins. It fights bacteria in your body.


Cloxacillin is used to treat many different types of infections caused by staphylococcus bacteria ("staph" infections).


Cloxacillin may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about Cloxapen (cloxacillin)?


Take all of the cloxacillin that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated. Do not break, chew, open, or crush the capsules. Swallow them whole. Cloxacillin may decrease the effectiveness of birth control pills. Use a second method of birth control while taking cloxacillin to protect against pregnancy.

Who should not take Cloxapen (cloxacillin)?


If you have ever had an allergic reaction to another penicillin or to a cephalosporin, do not take cloxacillin unless your doctor is aware of your allergy and monitors your therapy.

Before taking this medication, tell your doctor if you have kidney disease, stomach or intestinal disease, or infectious mononucleosis. You may not be able to take cloxacillin because of an increased risk of side effects.


If you are a diabetic, some glucose urine tests may give false positive results while you are taking cloxacillin.


Cloxacillin is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not, however, take cloxacillin without first talking to your doctor if you are pregnant. It is not known whether cloxacillin passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take Cloxapen (cloxacillin)?


Take cloxacillin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.


Take each dose with a full glass of water. Take cloxacillin on an empty stomach 1 hour before or 2 hours after meals.

Do not drink juice or carbonated beverages (soda) with your dose of cloxacillin. These beverages will decrease the effectiveness of the drug.


Cloxacillin should be taken at evenly spaced intervals throughout the day and night to keep the level in your blood high enough to treat the infection.


Do not crush, chew, or open the capsules. Swallow them whole. Shake the suspension well before measuring a dose. To ensure that you get a correct dose, measure the liquid form of cloxacillin with a dose-measuring spoon or cup, not a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one. Take all of the cloxacillin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Store the capsules at room temperature and store the suspension in the refrigerator for longer use. The suspension is good for 14 days if it is stored in the refrigerator. Throw away any unused liquid after this amount of time.

What happens if I miss a dose?


Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.


If you have only missed one dose, you can take the rest of your scheduled doses for the day at evenly spaced intervals.


What happens if I overdose?


Seek emergency medical attention.

Symptoms of an cloxacillin overdose include muscle spasms or weakness, pain or twitching, pain in the fingers or toes, loss of feeling in the fingers or toes, seizures, confusion, coma, and agitation.


What should I avoid while taking Cloxapen (cloxacillin)?


Alcohol may irritate your stomach if taken with cloxacillin, so use it with moderation.

Cloxapen (cloxacillin) side effects


If you experience any of the following serious side effects, stop taking cloxacillin and seek emergency medical attention:

  • an allergic reaction (shortness of breath; closing of your throat; hives; swelling of your lips, face, or tongue; rash; or fainting);




  • seizures;




  • severe watery diarrhea and abdominal cramps; or




  • unusual bleeding or bruising.



Other, less serious side effects maybe more likely to occur. Continue to take cloxacillin and talk to your doctor if you experience



  • mild nausea, vomiting, diarrhea, or abdominal pain;




  • white patches on the tongue (thrush/yeast infection);




  • itching or discharge of the vagina (vaginal yeast infection); or




  • black, "hairy" tongue or sore mouth or tongue.



Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


What other drugs will affect Cloxapen (cloxacillin)?


Some drugs may decrease the effects of cloxacillin and prevent it from properly treating your infection. Before taking cloxacillin, tell your doctor if you are taking any of the following drugs:



  • cholestyramine (Questran) or colestipol (Colestid); or




  • another antibiotic (for the same or for a different infection) such as erythromycin (Ery-Tab, E-Mycin, E.E.S., others), tetracycline (Sumycin, others), minocycline (Minocin), doxycycline (Doryx, Vibramycin, others), or any other.




Cloxacillin may decrease the effectiveness of birth control pills. Use a second method of birth control while taking cloxacillin to protect against pregnancy.

Cloxacillin increases the effects of methotrexate, and you may need a dose adjustment during therapy with cloxacillin.


Cloxacillin also increases the side effects of allopurinol (Zyloprim) and may cause a rash.


Probenecid (Benemid) increases the effects of cloxacillin. These drugs may be used together for this purpose; however, be sure your doctor is aware if you are taking probenecid. You may need a lower dose of cloxacillin.


Drugs other than those listed here may also interact with cloxacillin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.



More Cloxapen resources


  • Cloxapen Side Effects (in more detail)
  • Cloxapen Use in Pregnancy & Breastfeeding
  • Drug Images
  • Cloxapen Drug Interactions
  • Cloxapen Support Group
  • 0 Reviews for Cloxapen - Add your own review/rating


  • Cloxapen Advanced Consumer (Micromedex) - Includes Dosage Information



Compare Cloxapen with other medications


  • Bladder Infection
  • Pneumonia
  • Skin and Structure Infection
  • Upper Respiratory Tract Infection


Where can I get more information?


  • Your pharmacist has additional information about cloxacillin written for health professionals that you may read.

What does my medication look like?


Cloxacillin is available generically and with a prescription in 250 and 500 mg capsules and in a suspension formulation of 120 mg per 5 mL (1 teaspoon). Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.


See also: Cloxapen side effects (in more detail)


Coricidin HBP Maximum Strength Flu


Generic Name: acetaminophen, chlorpheniramine, and dextromethorphan (a SEET a MIN oh fen, klor fen IR a meen, dex troe meth OR fan)

Brand Names: Coricidin HBP Maximum Strength Flu, Mapap Cough & Sinus Formula, Triaminic Flu Cough & Fever, Triaminic Multi-Symptom Fever, Tylenol Childrens Plus Cough & Runny Nose


What is Coricidin HBP Maximum Strength Flu (acetaminophen, chlorpheniramine, and dextromethorphan)?

Acetaminophen is a pain reliever and fever reducer.


Chlorpheniramine is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.


Dextromethorphan is a cough suppressant. It affects the cough reflex in the brain that triggers coughing.


The combination of acetaminophen, chlorpheniramine, and dextromethorphan is used to treat headache, fever, body aches, cough, runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.


This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, chlorpheniramine, and dextromethorphan may also be used for purposes not listed in this medication guide.


What is the most important information I should know about this medicine?


Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Do not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You should not use this medicine if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate. Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid. Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects. Avoid drinking alcohol. It may increase your risk of liver damage while you are taking acetaminophen, and can increase certain side effects of chlorpheniramine. Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

What should I discuss with my healthcare provider before taking this medicine?


You should not use this medicine if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate. Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid. Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:



  • liver disease, cirrhosis, a history of alcoholism, or if you drink more than 3 alcoholic beverages per day;




  • a blockage in your digestive tract (stomach or intestines);




  • kidney disease;




  • cough with mucus, or cough caused by emphysema or chronic bronchitis;




  • enlarged prostate or urination problems; or




  • if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).




It is not known whether acetaminophen, chlorpheniramine, and dextromethorphan will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant. Acetaminophen, chlorpheniramine, and dextromethorphan may pass into breast milk and may harm a nursing baby. Antihistamines may also slow breast milk production. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Artificially sweetened cold medicine may contain phenylalanine. If you have phenylketonuria (PKU), check the medication label to see if the product contains phenylalanine.


How should I take this medicine?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. This medicine is usually taken only for a short time until your symptoms clear up.


Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Measure liquid medicine with a special dose measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose measuring device, ask your pharmacist for one.


Do not take for longer than 7 days in a row. Stop taking the medicine and call your doctor if you still have a fever after 3 days of use, you still have pain after 7 days (or 5 days if treating a child), if your symptoms get worse, or if you have a skin rash, ongoing headache, or any redness or swelling.


If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days. Store at room temperature away from moisture and heat. Do not allow liquid medicine to freeze.

What happens if I miss a dose?


Since this medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.


Overdose symptoms may also include severe forms of some of the side effects listed in this medication guide.


What should I avoid while taking this medicine?


Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP. Avoid drinking alcohol. It may increase your risk of liver damage while you are taking acetaminophen, and can increase certain side effects of chlorpheniramine. This medicine may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

This medicine side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • chest pain, rapid pulse;




  • fast, slow, or uneven heart rate;




  • severe dizziness or anxiety, feeling like you might pass out;




  • severe headache;




  • mood changes, confusion, hallucinations, severe nervousness;




  • tremor, seizure (convulsions);




  • fever, easy bruising or bleeding, unusual weakness;




  • urinating less than usual or not at all;




  • nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes); or




  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, uneven heartbeats, seizure).



Less serious side effects may include:



  • dizziness, drowsiness, mild headache;




  • dry mouth, nose, or throat;




  • constipation, diarrhea, mild nausea, upset stomach;




  • blurred vision;




  • feeling restless or irritable; or




  • sleep problems (insomnia).



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect this medicine?


Ask a doctor or pharmacist before using this medicine if you regularly use other medicines that make you sleepy (such as narcotic pain medication, sedatives, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by chlorpheniramine.

Ask a doctor or pharmacist if it is safe for you to use acetaminophen, chlorpheniramine, and dextromethorphan if you are also using any of the following drugs:



  • leflunomide (Arava);




  • topiramate (Topamax);




  • zonisamide (Zonegran);




  • an antibiotic, antifungal medicine, sulfa drug, or tuberculosis medicine;




  • an antidepressant;




  • birth control pills or hormone replacement therapy;




  • bladder or urinary medications;




  • blood pressure medication;




  • a bronchodilator;




  • cancer medicine;




  • cholesterol-lowering medications such as Lipitor, Niaspan, Zocor, Vytorin, and others;




  • gout or arthritis medications (including gold injections);




  • HIV/AIDS medication;




  • medication for nausea and vomiting, stomach ulcers, or irritable bowel syndrome;




  • medicines to treat psychiatric disorders;




  • an NSAID such as Advil, Aleve, Arthrotec, Cataflam, Celebrex, Indocin, Motrin, Naprosyn, Treximet, Voltaren, others; or




  • seizure medication.



This list is not complete and there may be other drugs that can affect acetaminophen, chlorpheniramine, and dextromethorphan. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.



More Coricidin HBP Maximum Strength Flu resources


  • Coricidin HBP Maximum Strength Flu Side Effects (in more detail)
  • Coricidin HBP Maximum Strength Flu Use in Pregnancy & Breastfeeding
  • Coricidin HBP Maximum Strength Flu Drug Interactions
  • 0 Reviews for Coricidin HBP Maximum Strength Flu - Add your own review/rating


Compare Coricidin HBP Maximum Strength Flu with other medications


  • Cold Symptoms
  • Influenza


Where can I get more information?


  • Your pharmacist can provide more information about acetaminophen, chlorpheniramine, and dextromethorphan.

See also: Coricidin HBP Maximum Strength Flu side effects (in more detail)


Sunday 1 April 2012

Limbitrol


Generic Name: amitriptyline and chlordiazepoxide (a mi TRIP ti leen and klor dye az e POX ide)

Brand Names: Limbitrol, Limbitrol DS


What is Limbitrol (amitriptyline and chlordiazepoxide)?

Amitriptyline is a tricyclic (try-SYE-klik) antidepressants. Amitriptyline affects chemicals in the brain that may become unbalanced.


Chlordiazepoxide is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Chlordiazepoxide affects chemicals in the brain that may become unbalanced and cause anxiety.


The combination of amitriptyline and chlordiazepoxide is used to treat depression and anxiety.


Amitriptyline and chlordiazepoxide may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Limbitrol (amitriptyline and chlordiazepoxide)?


You should not use this medication if you have recently had a heart attack, or if you are allergic to amitriptyline (Elavil), chlordiazepoxide (Librium), or to Valium, Xanax, or any other benzodiazepine. Do not use this medication if you have taken an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the last 14 days. Amitriptyline and chlordiazepoxide can harm an unborn baby or cause birth defects. Do not use amitriptyline and chlordiazepoxide if you are pregnant.

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.



Video: Treatment for Depression







Treatments for depression are getting better everyday and there are things you can start doing right away.





Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Do not drink alcohol while taking this medication.

What should I discuss with my healthcare provider before taking Limbitrol (amitriptyline and chlordiazepoxide)?


You should not use this medication if you have recently had a heart attack, or if you are allergic to amitriptyline (Elavil), chlordiazepoxide (Librium), or to any benzodiazepine such as alprazolam (Xanax), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax). Do not use this medication if you have taken an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the last 14 days.

To make sure you can safely take amitriptyline and chlordiazepoxide, tell your doctor if you have any of these other conditions:



  • epilepsy or seizure disorder;




  • a thyroid disorder;




  • kidney or liver disease;




  • heart disease;




  • bipolar disorder (manic-depression);




  • a history of suicidal thoughts or behavior;




  • history of drug or alcohol addiction;




  • narrow-angle glaucoma; or




  • problems with urination.



You may have thoughts about suicide while taking an antidepressant, especially if you are younger than 24 years old. Tell your doctor if you have worsening depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.


Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.


This medication can harm an unborn baby or cause birth defects. Do not use amitriptyline and chlordiazepoxide if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use effective birth control while you are using this medication. It is not known whether this medication passes into breast milk or if it could harm a nursing baby. You should not breast-feed while taking amitriptyline and chlordiazepoxide.

The sedative effects of this medication may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking amitriptyline and chlordiazepoxide.


How should I take Limbitrol (amitriptyline and chlordiazepoxide)?


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.


It may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment. If you need surgery, tell the surgeon ahead of time that you are using amitriptyline and chlordiazepoxide. You may need to stop using the medicine for a short time.

If you use this medication long-term, your blood will need to be tested on a regular basis. Do not miss any scheduled appointments.


Do not stop using amitriptyline and chlordiazepoxide suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using the medicine. Amitriptyline and chlordiazepoxide may be habit-forming and should be used only by the person it was prescribed for. Never share this medication with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Store at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Benzodiazepines are drugs of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

See also: Limbitrol dosage (in more detail)

What happens if I miss a dose?


Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline and chlordiazepoxide can be fatal, especially if taken with alcohol.

Overdose symptoms may include irregular heartbeats, extreme drowsiness, overactive reflexes, stiff muscles, dilated pupils, vomiting, feeling hot or cold, feeling like you might pass out, or seizure (convulsions).


What should I avoid while taking Limbitrol (amitriptyline and chlordiazepoxide)?


Do not drink alcohol. Amitriptyline and chlordiazepoxide can increase the effects of alcohol, which could be dangerous. This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Limbitrol (amitriptyline and chlordiazepoxide) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have a serious side effect such as:

  • confusion, hallucinations, unusual thoughts or behavior;




  • feeling light-headed, fainting;




  • seizure (convulsions);




  • weak or shallow breathing;




  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling; or




  • sudden numbness or weakness (especially on one side of the body), headache, confusion, problems with vision, speech, or balance.



Less serious side effects may include:



  • dry mouth, stuffy nose, blurred vision;




  • dizziness, drowsiness;




  • feeling restless or tired;




  • constipation, bloating, loss of appetite;




  • strange dreams or nightmares; or




  • decreased sex drive, impotence, or difficulty having an orgasm.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Limbitrol (amitriptyline and chlordiazepoxide)?


Before taking this medicine, tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft).


Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures or anxiety can add to sleepiness caused by amitriptyline and chlordiazepoxide. Tell your doctor if you regularly use any of these medicines, or any other antidepressant.

Many drugs can interact with amitriptyline and chlordiazepoxide. Below is just a partial list. Tell your doctor if you are using:



  • celecoxib (Celebrex);




  • cimetidine (Tagamet);




  • darifenacin (Enablex);




  • ropinirole (Requip);




  • terbinafine (Lamisil);




  • ADHD medications (Adderall, Ritalin, Strattera);




  • anti-malaria medication such as chloroquine (Arelan), hydroxychloroquine (Plaquenil, Quinaprox), or quinine (Qualaquin);




  • cancer medications such as gefitinib (Iressa), imatinib (Gleevec), or nilotinib (Tasigna);




  • a heart rhythm medication such as amiodarone (Cordarone, Pacerone), flecainide (Tambocor), propafenone (Rythmol), or quinidine (Quin-G);




  • HIV medication such as delavirdine (Rescriptor) or ritonavir (Norvir);




  • medicine to treat or prevent nausea and vomiting, such as metoclopramide (Reglan) or promethazine (Pentazine, Phenergan);




  • medicine to treat psychiatric disorders, such as aripiprazole (Abilify), chlorpromazine (Thorazine), fluphenazine (Permitil), haloperidol (Haldol), perphenazine (Trilafon), or thioridazine (Mellaril);




  • a narcotic such as methadone (Methadose, Dolophine) or propoxyphene (Darvon, Darvocet).




This list is not complete and there are many other drugs that can interact with amitriptyline and chlordiazepoxide. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

More Limbitrol resources


  • Limbitrol Side Effects (in more detail)
  • Limbitrol Dosage
  • Limbitrol Use in Pregnancy & Breastfeeding
  • Drug Images
  • Limbitrol Drug Interactions
  • Limbitrol Support Group
  • 2 Reviews for Limbitrol - Add your own review/rating


  • Limbitrol Prescribing Information (FDA)

  • Limbitrol Advanced Consumer (Micromedex) - Includes Dosage Information

  • Limbitrol DS MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Limbitrol with other medications


  • Anxiety
  • Depression


Where can I get more information?


  • Your pharmacist can provide more information about amitriptyline and chlordiazepoxide.

See also: Limbitrol side effects (in more detail)